摘要
目的:探讨真人养脏汤加穴位贴敷治疗结直肠癌术后腹泻的临床效果。方法:选取78例结直肠癌术后腹泻患者作为研究对象,随机分为对照组(34例)和观察组(44例)。对照组给予盐酸洛哌丁胺口服,首次剂量为4 mg,之后2 mg/次维持;观察组给予真人养脏汤加穴位贴敷治疗。观察比较两组治疗总有效率、复发率及不良反应发生情况。结果:对照组总有效率为85.29%;观察组总有效率为86.36%。两组总有效率比较,差异无统计学意义(x2=0.018,P>0.05)。对照组复发16例,复发率为55.17%;观察组复发5例,复发率为13.16%。观察组复发率明显较对照组低,差异具有统计学意义(x2=13.492,P<0.05)。两组治疗过程中均无严重不良反应事件发生。结论:真人养脏汤加穴位贴敷治疗结直肠癌术后腹泻可以有效改善患者肠道功能,控制复发,远期效果较好,安全性高,值得临床推广应用。
Objective:To explore the effects of zhenren yangzang decoction combined with acupoint application on postoperative diarrhea of colorectal cancer. Methods:78 patients with postoperative diarrhea of colorectal cancer were selected and randomly divided into control group (34 cases) and observation group (44 cases). The control group was treated with loperamide hydrochloride with the first dose of 4 mg, following by a maintenance dose of 2 mg. The observation group was treated with zhenren yangzang decoction combined with acupoint application. The total effective rates, recurrence and side effects were compared between the two groups. Results: The total effective rate of the control group was 85.29%, the observation group 86.36%, The difference was not statistically significant(x2=0.018, P>0.05).16 cases(55.17%)recurred in control group and 5 cases(13.16%)recurred in observation group. The recurernce rate of observation group was significantly lower than that of control group. The difference was statisticaly significant(x2=13.492,P<0.05). There were no serious side effects in both two groups. Conclusions:Zhenren yangzang decoction combined with acupoint application for postoperative diarrhea of colorectal cancer could effectively improve the intestinal function, control recurrence. It has good long-term effects and with high security, so it deserves the clinical expansion.
出处
《中医临床研究》
2014年第30期128-130,共3页
Clinical Journal Of Chinese Medicine
关键词
真人养脏汤
穴位贴敷
结直肠癌
腹泻
治疗效果
Zhenren yangzang decoction
Acupoint application
Colorectal cancer
Diarrhea
Curative effect