摘要
目的比较奥曲肽同生长抑素治疗肝硬化食道静脉破裂出血的临床疗效和不良反应。方法选取我院收治的510例肝硬化食道静脉破裂出血患者作为研究对象。随机分为奥曲肽治疗组和生长抑素治疗组。观察两组的止血效果及不良反应。结果奥曲肽治疗组止血有效率为84.71%,其不良反应率为6.27%;而生长抑素治疗组止血有效率为87.84%,其不良反应率为7.84%。两组间有效率及不良反应率差异均无统计学意义(P>0.05)。结论在治疗肝硬化食道静脉破裂出血中,奥曲肽与生长抑素均可收到较好疗效,可在临床推广使用。
Objective To compare octreotide’ s and somatostatin’ s clinical curative effects on the treatment of cirrhosis esophagus vein rupture hemorrhage and their adverse reactions. Methods Chose 510 cases of these cirrhosis esophagus vein rupture hemorrhage patients who have been admitted at our hospital as study objectives,divided them into octreotide group and somatostatin group randomly. Observed these two groups’ hemostatic effects and adverse reactions. Results Octreotide group’s hemostatic effective rate was 84. 71%,and its happening rate of adverse reactions was 6. 27%,while somatostatin group’ s hemostatic effective rate was 87. 84%,it s happening rate of adverse reactions was 7. 84%,there were no significant differences between these two groups. Conclusion With regard to the treatment of cirrhosis esophagus vein rupture hemorrhage,both octreotide and somatostatin have good clinical curative effects,they two are worthy of clinical promotion and application.
出处
《四川医学》
CAS
2014年第9期1193-1195,共3页
Sichuan Medical Journal
关键词
奥曲肽
生长抑素
肝硬化
octreotide
somatostatin
cirrhosis
