摘要
目的：探讨东莞地区维持性腹膜透析患者腹膜透析相关性葡萄球菌腹膜炎的发病率及其相关危险因素。方法选取中山大学附属东华医院腹膜透析中心192例患者为研究对象。根据腹膜透析液培养结果将患者分成腹膜炎组与对照组。腹膜透析相关性葡萄球菌腹膜炎相关危险因素分析采用多因素Logistic回归。结果192例患者中，共有16例（8．3％）患者发生腹膜透析相关性葡萄球菌腹膜炎，致病菌以表皮葡萄球菌为主，治愈率为81．25％，病死率为6．25％。高龄（OR＝1．35，95％CI 为1．16∽7．68，P＝0．026）、糖尿病（OR＝3．34，95％CI 为1．90∽6．54，P＜0．01）、低血红蛋白（OR＝1．68，95％CI 为1．21∽6．48， P＝0．022）及低清蛋白血症（OR＝1．04，95％CI为1．02∽1．07，P＝0．036）是腹膜透析相关性葡萄球菌腹膜炎的相关危险因素。结论东莞地区腹膜透析相关性葡萄球菌腹膜炎发病率较高，高龄、低血红蛋白、糖尿病及低清蛋白血症是其相关危险因素。
Objective To study the incidence and risk factors of peritoneal dialysis-related Staphylococcus peritonitis in continu-ous ambulatory peritoneal dialysis（CAPD）patients in Dongguan.Methods 192 CAPD cases with peritoneal dialysis-related perito-nitis in the Affiliated Donghua Hospital of Sun Yet-Sen University were enrolled as subjects and divided into peritonitis group and control group,according to the culture results of peritoneal dialysis fluid.The associated risk factors of peritoneal dialysis-related Staphylococcus peritonitis were investigated through Logistic regression analysis.Results The incidence of peritoneal dialysis-re-lated Staphylococcus peritonitis was 8.3%（16 cases）.The main pathogens were Staphylococcus spidermidis.The cure rate was 81.25%,and the mortality was 6.25%.The advanced age（OR= 1.35,95%CI 1.16-7.68,P= 0.026）,diabetes（OR= 3.34,95%CI 1.90-6.54,P〈0.01）,lower hemoglobin（OR= 1.68,95%CI 1.21-6.48,P= 0.022）and lower albumin（OR= 1.04,95%CI 1.02-1.07,P= 0.036）were associated risk factors of peritoneal dialysis-related Staphylococcus peritonitis.Conclusion The inci-dence of peritoneal dialysis-related Staphylococcus peritonitis is high in Dongguan,and advanced age,diabetes,lower hemoglobin and lower albumin are associated risk factors of it.
出处
《国际检验医学杂志》
CAS
2014年第12期1577-1579,共3页
International Journal of Laboratory Medicine
关键词
维持性腹膜透析
葡萄球菌
危险因素
continuous ambulatory peritoneal dialysis
Staphylococcus
associated factors
