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B组碳青霉烯酶基因bla_(VIM-2)的基因环境分析

Analysis of the genetic context of class B carbapenemase gene bla_(VIM-2)
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摘要 目的探讨blaVIM-2基因的基因环境。方法采用"Blast"比对分析GenBank数据库中blaVIM-2基因所处的基因环境。分析blaVIM-2基因分布的种属、地域及基因环境特征。结果所有的blaVIM-2基因都以基因盒的形式定位于Ⅰ型整合子内部。blaVIM-2基因大多在假单胞菌属中检出,偶尔在肠杆菌中检出。结论不同国家、不同菌属报道的blaVIM-2的基因环境有极大的相似性。 Objective To analyze the genetic context of blaVIM-2 .Methods "Blast"was used to analyze sequences harboring blaVIM-2 submitted to GenBank database.Results blaVIM-2 mostly embedded in class Ⅰ integron in the form of gene cassettes andblaVIM-2 gene was most commonly detected in Pseudomonas and occasionally detected in Enterobacter.Conclusion blaVIM-2 gene reported in different species and recovered from geometrical locations could be with some common characteristics.
出处 《国际检验医学杂志》 CAS 2014年第12期1529-1530,共2页 International Journal of Laboratory Medicine
基金 传染病预防控制国家重点实验室面上项目(2012SKLID205)
关键词 VIM-2 基因 碳青霉烯酶 肠杆菌属 假单胞菌属 blaVIM-2 carbapenemase Entertobacter Pseudomonas
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