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Has the cardiac stem cell controversy settled down?

Has the cardiac stem cell controversy settled down?
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摘要 Although the human adult heart was considered a terminally differentiated organ and incapable of renewal after injury or with aging for almost a century, recent studies have shown that the heart is capable of new cardiomyocyte formation and possesses varying degrees of regenerative potential throughout mammalian life. However, whether the cardiac stem cells (CSC) or the pre-existing cardiomyocytes con- tribute to the new cardiomyocyte formation remains con- troversial. Although the human adult heart was considered a terminally differentiated organ and incapable of renewal after injury or with aging for almost a century,recent studies have shown that the heart is capable of new cardiomyocyte
出处 《Science China(Life Sciences)》 SCIE CAS 2014年第9期949-950,共2页 中国科学(生命科学英文版)
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  • 2Ellison GM, Vicinanza C, Smith AJ, Aquila I, Leone A, Waring CD, Henning BJ, Stirparo GG, Papait R, Scarfò M, Agosti V, Viglietto G, Condorelli G, Indolfi C, Ottolenghi S, Torella D, Nadal-Ginard B. Adult c-kit(pos) cardiac stem cells are necessary and sufficient for functional cardiac regeneration and repair. Cell, 2013, 154: 827-842.
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