摘要
目的:阐释慢性乙型肝炎(chronic hepatitis B,CHB)口干症状的临床意义.方法:2011-11/2012-09首都医科大学附属北京中医医院肝病门诊就诊CHB患者463例,采用前瞻性调查方法,研究CHB口干程度、口干出现率与病情程度的关系,CHB口干症状出现率与病位证素的关系,口干程度与家族史、病情程度、病性证素的关系.结果:(1)口干是CHB患者的常见临床症状;(2)CHB家族史的患者口干程度严重,P<0.05;(3)CHB口干程度与病情程度显著相关,相关系数r为0.185,P<0.05.口干出现率从健康人-CHB轻度-CHB中度-CHB重度逐渐增高,各组间存在显著差异(P<0.05).口干程度从健康人-CHB轻度-CHB中度-CHB重度逐渐增高,CHB中度和重度患者较健康人口干程度显著增高(P<0.05).CHB重度患者较中度患者口干程度显著增高(P<0.05);(4)口干与CHB肾、肝病位有密切关系(P<0.05).口干程度与CHB病性证素热证、阴虚的相关系数最高(P<0.05).结论:口干症状是CHB肝肾阴虚证的重要诊断依据,与乙型肝炎家族史密切相关,对CHB证候的辨识具有积极的指导意义.
AIM： To investigate the epidemic characteristics of dry month in patients with chronic hepatitis B （CHB）. METHODS： Clinical data of 463 patients with CHB were analyzed, including clinical symp- toms and laboratory test results. All data were analyzed by the t-test and 2 test. RESULTS： Dry month was prevalent in patients with CHB, especially in those with a family histo- ry. Dry month was closely related with the severity of the disease, kidney syndrome, liver syndrome, heat syndrome and yin deficiency syndrome. CONCLUSION： Dry month is an important di- agnosis basis for liver and kidney yin deficiencysyndrome, and can help identify various syn- dromes in patients with CHB.
出处
《世界华人消化杂志》
CAS
北大核心
2014年第21期3122-3126,共5页
World Chinese Journal of Digestology
基金
北京市教委基金资助项目
No.KM201110025011~~
关键词
慢性乙型肝炎
口干
肝肾阴虚
家族史
病情程度
Chronic hepatitis B
Dry mouth
Liverand kidney yin deficiency syndrome
Family history
Severity
