摘要
目的:比较低频电穴位刺激与常规西药治疗脑卒中后失眠患者的临床疗效差异。方法:将120例脑卒中后失眠患者随机分为低频电刺激组、药物组及安慰剂组,每组40例(安慰剂组剔除1例)。低频电刺激组采用低频脉冲电治疗仪对大椎、肾俞穴进行刺激,每天1次,15天为一疗程,治疗2个疗程;药物组口服艾司唑仑,每次1mg,安慰剂组口服淀粉胶囊,每次1粒,均为每晚睡前服用,连续口服15天为一疗程,均治疗2个疗程。观察各组治疗前后匹兹堡睡眠质量指数(PSQI)变化情况和临床疗效。结果:各组患者治疗后PSQI评分均降低(均P<0.01),低频电穴位刺激组、药物组较安慰剂组评分降低更显著(均P<0.01);低频电刺激组、药物组和安慰剂组总有效率分别为95.0%(38/40)、92.5%(37/40)和17.9%(7/39),低频电穴位刺激组、药物组疗效均明显优于安慰剂组(均P<0.01)。结论:低频电穴位刺激治疗脑卒中后失眠安全有效,与口服艾司唑仑疗效相当。
Objective To compare the difference in the clinical efficacy on post-stroke insomnia between the low-frequency electric stimulation at the acupoints and the conventional western medication. Methods One hun- dred and twenty patients of post-stroke insomnia were randomized into a low-frequency electric stimulation group, a medication group and a placebo group, 40 cases in each one. In the low-frequency electric stimulation group, the low-frequency electric-pulsing apparatus was used at Dazhui （GV 14） and Shenshu （BL 23）, once a days the treat- ment of 15 days made one session and 2 sessions were required. In the medication group, estazolam was taken orally, 1 mg each time. In the placebo group, starch capsules were taken orally, 1 capsule each time. All the drugs were taken before sleep every night, continuously for 15 days as one session, and 2 sessions were required. PSQI changes and clinical efficacy were observed before and after treatment in each group. Results Pitlsburgh sleep quality index （PSQI） score was reduced in every group after treatment （all P〈0.01）. In the low-frequency electric stimulation group and medication group, the score was reduced much more significantly as compared with the pla- cebo group （both P〈0.01）. In the placebo group, 1 case was rejected. The total effective rates were 95.0% （38/ 40）, 92.50%（37/40） and 17.9 %（7/39） in the low-frequency electric stimulation group, medication group and placebo group separately. The efficacy in the low-frequency electric stimulation group and medication group was better apparently than that in the placebo group （both P〈0.01）. Conclusion The low-frequency electric stimulation at the acu- points effectively and safely treats post-stroke insomnia and the efficacy of it is similar to that of estazolam.
出处
《中国针灸》
CAS
CSCD
北大核心
2014年第8期747-750,共4页
Chinese Acupuncture & Moxibustion
基金
武汉市卫生局资助课题项目:WZ14Z18
关键词
失眠
脑卒中
低频电穴位刺激
随机对照研究
insomnia
stroke
low-frequency electric stimulation at the acupoints
randomized controlled trial（RCT）
