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颅内压初始值对颅脑创伤患者预后的预测价值 被引量:4

Predictive value of initial intracranial pressure for the prognosis of patients with traumatic brain injury
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摘要 共118例颅脑创伤患者通过颅内压监测,评价颅内压初始值作为判断预后指标的临床预测价值.结果显示,颅内压初始值[受试者工作特征(ROC)曲线下面积为0.725;95%CI:0.635 ~ 0.815]与患者入院时Glasgow昏迷量表评分(ROC曲线下面积为0.716; 95%CI:0.616~0.816)和Marshall分级(ROC曲线下面积为0.690;95%CI:0.593~0.787)等项指标具有相似的预后预测价值;经Logistic回归分析,颅内压初始值与不良预后相关(OR=0.943,95%CI:0.899 ~ 0.988;P=0.014).提示颅内压初始值可以作为颅脑创伤患者不良预后的独立预测因素. This paper aims to investigate the predictive value of initial intracranial pressure (ICP) for the prognosis of patients with traumatic brain injury (TBI).A prospective observational study was conducted in 118 TBI patients with ICP monitoring.The initial ICP [receiver operating characteristic (ROC) area =0.725; 95%CI:0.635-0.815] was similar to admission Glasgow Coma Scale (GCS; ROC area =0.716; 95% CI:0.616-0.816) or Marshall classification (ROC area =0.690; 95% CI:0.593-0.787) in predicting the prognosis of TBI patients.A Logistic regression analysis showed that initial ICP was associated with poor prognosis in TBI patients (OR =0.943,95%CI:0.899-0.988; P =0.014).The initial ICP in TBI patients could be used as an independent predictor of TBI patients' outcomes.
出处 《中国现代神经疾病杂志》 CAS 2014年第8期726-729,共4页 Chinese Journal of Contemporary Neurology and Neurosurgery
关键词 颅内压 颅脑损伤 预后 Intracranial pressure Craniocerebral trauma Prognosis
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  • 1Chesnut RM,Temkin N,Carney N,Dikmen S,Rondina C,Videtta W,Petroni G,Lujan S,Pridgeon J,Barber J,Machamer J,Chaddock K,Celix JM,Cherner M,Hendrix T;Global Neurotrauma Research Group.A trial of intracranial-pressure monitoring in traumatic brain injury.N Engl J Med,2012,367:2471-2481.
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