摘要
目的研究区域动脉灌注(local arterial infusion,LAI)给药治疗重症急性胰腺炎的效果。方法 46例重症急性胰腺炎患者,随机分为两组:A组(治疗组)20例,采用区域动脉灌注治疗;B组(对照组)26例,采用常规静脉给药,比较两组疗效。结果 A组血淀粉酶下降较B组迅速(P<0.05),血液流变学的比较显示,A组的血液粘滞度下降更明显,差异显著(P<0.05)。结论LAI对重症急性胰腺炎是安全有效的治疗手段,优于经静脉途径治疗。
Objective To evaluate the effect of local arterial infusion（LAI） of medicine on severe acute pancreatitis（SAP）. Methods 46 case of SAP were randomly divided into two groups： Group A （treatment group, n = 20 ） received LAI therapy and Group B （ control group, n = 26 ） received only the routine therapy. The curative effects of the two groups were compared. Results The amylase in blood reduced more quickly in the treatment group than that of the control group（ P 〈 0.05 ）. The blood rheology index was significantly improved in the treatment group （ P 〈 0.05 ）. Conclusion LAI is an effective and safe treatment for SAP, and is more effective than the intravenous injection.
出处
《中国现代手术学杂志》
2014年第4期263-265,共3页
Chinese Journal of Modern Operative Surgery
关键词
胰腺炎
局部灌注
动脉
治疗结果
pancreatitis
regional perfusion,arteries
treatment outcome
