摘要
通过分析急性呼吸道感染(Acute respiratory tract infection,ARTI)患儿腺病毒(Adenovirus,ADV)的流行病学特点及其临床特征,为临床早期诊治提供理论依据。2011年1月至2012年12月在常州市第二人民医院住院的3480例ARTI患儿,采集鼻咽部分泌物,采用直接免疫荧光法检测ADV抗原。两年共检出ADV阳性病例80例,阳性率为2.30%(80/3 480);2011年感染率显著高于2012年。ADV夏秋季感染率较高,冬春季感染率较低;1岁以内ADV感染率较低,仅为1.14%,其他年龄段感染率明显升高。ADV是常州地区ARTI患儿重要病原体,在1岁以上儿童中多发,呈常年散发状态,夏秋季节感染率高;ADV感染临床表现多,重症患儿多,危害大。
By analyzing the epidemiological and clinical features of adenovirus in children with acute respiratory tract infection（ARTI）,we provide a theoretical basis for early clinical diagnosis and treatment.Nasopharyngeal secretions were collected from 3480children with ARTI,who were hospitalized at the No.2Hospital of Changzhou from January 2011to December 2012.Adenovirus were detected using direct immunofluorescence assays.A total of 80samples were positive for adenovirus（2.30%）.The rate of adenovirus infection during 2011was significantly higher than that in 2012,and the infection rate was higher in summer and autumn than in winter and spring.The infection rate was 1.14%among children aged＆lt;1-yearold and the rates were higher among children in other age ranges.Adenovirus was found to be an important ARTI pathogen in children in Changzhou,mainly affecting children older than 1year.ADV infections have various clinical presentations,but affected children tend to be severely ill with poor outcomes.
出处
《病毒学报》
CAS
CSCD
北大核心
2014年第4期408-411,共4页
Chinese Journal of Virology
关键词
腺病毒
急性呼吸道感染
儿童
病原体
Adenovirus
Acute respiratory tract infection
Child
Pathogen
