摘要
微粒是细胞衍生的微小囊泡,携带有母细胞来源的多种物质,能与靶细胞发挥相互作用。微粒对急性肺损伤(ALI)的多种病理生理过程具有双重调节作用,能够通过多种机制影响炎性反应、凝血功能、血管通透性、内皮细胞凋亡等。因此,微粒对ALI的发生发展具有重要意义。
Microparticles, a kinds of small vesicles derived from the mother cells with a variety of contents, have been reported to involve in a variety of pathophysiological processes. The variety of contents in microparticles also can affect the coagulation function and inflammation. And microparticles can also influence the apoptosis of endothelial cells and the function of vascular harrier through various mechanisms. Therefore, microparticles have great significance on the occurrence and progress of acute lung injury.
出处
《基础医学与临床》
CSCD
北大核心
2014年第8期1138-1141,共4页
Basic and Clinical Medicine
基金
国家自然科学基金(81301625)
湖南省科技计划(2013SK3114)
南华大学博士启动基金(2012XQD27)
关键词
微粒
急性肺损伤
炎性反应
microparticles
acute lung injury
inflammation
