摘要
目的:探讨低蛋白饮食联合α-酮酸对延缓老年慢性肾功能衰竭(CRF)患者的病情进展、改善营养状况方面的作用。方法:150例老年CRF患者随机分为A、B、C组(各50例),A组予以常规蛋白饮食,B组予以低蛋白饮食,C组予以低蛋白饮食联合复方α-酮酸片,随访1年,监测患者的营养状况指标。结果:与B组患者相比,A、C组患者的营养状况指标升高;C组患者的肾小球滤过率下降速度明显低于A、B组患者。结论:低蛋白饮食联合α-酮酸治疗,可有效延缓老年慢性肾功能衰竭的进展,明显改善患者的营养状况,防止可能出现的营养不良。
OBJECTIVE：To investigate the effects of α-keto acid plus low-protein diet on delaying the disease progression and improve the nutritional status in elderly patients with chronic renal failure（CRF）. METHODS：150 CRF cases were randomized to three groups（group A,B,and C）of 50 each. Group A received routine protein diet,group B received low-protein diet and group C received low-protein diet plus α-keto acid. The patients were followed-up for one year and their nutrition status were monitored. RESULTS：Compared with group B,the nutritional indicators in group A and group C were significantly increased. The reduction speed of glomerular filtration rate in group C was significantly lower than in group A or group B. CONCLUSIONS：The combina-tion of α-keto acid and low-protein diet can effectively delay progression of chronic renal failure while significantly improve the nu-tritional status in elderly patients with CRF.
出处
《中国医院用药评价与分析》
2014年第7期594-596,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
