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风险产妇部分细胞因子血清水平分析

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摘要 目的:分析临产风险孕妇细胞因子白细胞介素-1β(IL-1β)、白细胞介素-6(IL-6)、白细胞介素-8(IL-8)、白细胞介素-10(IL-10)、肿瘤坏死因子-α(TNF-α)血清水平变化。方法:选择正常足月产妇40例(正常足月产妇组),风险产妇(包括早产、产后大出血和多胎妊娠)60例(风险产妇组),入院后于产前空腹采集静脉血;选择非孕健康妇女40例作为对照组。采用化学发光法检测各组血清IL-1β、IL-6、IL-8、IL-10和TNF-α水平,并统计分析各组各指标水平差异。结果:各组血清IL-1β和IL-8水平差异无统计学意义(P>0.05)。风险产妇组IL-6水平显著高于正常足月产妇组和对照组(P<0.01)。风险产妇组IL-10水平高于对照组(P<0.01),但低于正常足月产妇组(P<0.05)。风险产妇组与正常足月产妇组TNF-α水平差异无统计学意义(P>0.05),但均高于对照组(P<0.05)。结论:临产前检测细胞因子水平,对产妇风险评估有一定辅助参考价值。
作者 孔莹 刘泽金
出处 《微循环学杂志》 2014年第3期52-53,共2页 Chinese Journal of Microcirculation
关键词 产妇 细胞因子
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