摘要
目的了解哈尔滨市体检人群高尿酸血症（HUA）的患病情况及其危险因素。方法采用分层整群随机抽样方法对哈尔滨市3 551例参加健康体检的人群进行体格和生化检查。运用SPSS 20.0软件进行t检验和χ2检验,运用Logistic回归分析HUA的相关危险因素,P〈0.05为差异有统计学意义。结果所调查的人群中,男性血尿酸水平为（362.64±80.47）μmol/L,女性为（271.49±66.55）μmol/L,男性高于女性（t=36.89,P〈0.05）;男性HUA患病率为24.27%,女性为9.62%,男性高于女性（χ2=133.36,P〈0.05）,男性中,HUA患病率以19~29、30~39岁年龄组最高,分别为29.73%、29.74%;多因素logistic回归分析表明,男性、肥胖、血脂代谢异常和脂肪肝是HUA患病的主要危险因素（OR〉1,P〈0.05）。结论本调查研究体检人群男性HUA的患病率较高,且发病呈年轻化趋势;HUA与肥胖、血脂代谢异常及脂肪肝的关系密切。
Objective To understand the prevalence and related risk factors of hyperuricemia（HUA）among urban check-up residents in Harbin. Methods A stratified cluster sampling method was applied to randomly select 3551healthy check-up residents in Harbin.Physical as well as bio-chemical examinations were conducted.T-test and chi-square test were used for data analysis,and Logistic regression analysis was used to analyze risk factors. Results The average serum uric acid value was 362.64±80.47μmol/L for males which was higher than that in females（271.49±66.55μmol/L）（t=36.89,P＆lt;0.05）,The prevalence of hyperuricemia was 24.27%for males,which was also higher compared to that in females（9.62%）（χ2=133.36,P＆lt;0.05）.The prevalence of HUA was found to be the highest of 29.7% in male residents aged 19-39years.Logistic regression analysis revealed that male,obesity,dyslipidemia and fatty liver were the major risk factors（OR＆gt;1,P＆lt;0.05）of hyperuricemia. Conclusions The prevalence of hyperuricemia among urban check-up male residents is high,especially in young adults.Male,obesity,fatty liver and dyslipidemia are all closely associated with hypemricemia.
出处
《中国预防医学杂志》
CAS
2014年第4期328-331,共4页
Chinese Preventive Medicine
基金
国家自然科学基金(81373083)
