摘要
目的:了解接受柴苓降脂方治疗的脂肪肝患者痊愈后的状况和继续坚持积极非药物性干预的结果。方法:选择调查对象1140例,以痊愈后停药的第3个月、6个月和1年末连续召回原就诊医院复诊各1次,1年后以建立随访调查记录卡,在每年的2—3月份电话随访1次,连续跟踪随访7年。结果:进行积极非药物干预者820例(占被调查人数的72%),5年后脂肪肝复发5例其中合并其他相关疾病2例,与不坚持非药物干预者320例(占被调查人数的28%),5年后脂肪肝复发100例其中合并其他相关疾病60例比较,具有明显的统计学差异(P<0.01),坚持非药物干预者脂肪肝复发率和其他相关疾病的发病率明显低于不坚持非药物干预者。结论:接受柴苓降脂方治疗痊愈停药后,继续进行积极的非药物性干预对防止脂肪肝复发和减少相关代谢性疾病的发病率具有重要的临床意义。
OBJECTIVE To understand the state after full recovery of the fatty liver patients who were treated with ChaiL- ingjiangzhi decoction and the results of being treated with non drug intervention. METHODS 1140 cases of full recovery fatty liver patients were enrolled, and let them get a further consultation after three months, six months or one year. After one year the investigating minute cards were set up. From Feb. to Mar. every year called them once, and followed up for seven years. RESULTS In 820 full recovery patients who insisted on being treated by non drug intervention, there were 5 patients who had a relapse and 2 patients suffered other disease after 5 years. In 320 full recovery patients who did not insisted on being treated by non drug intervention, there were 100 patients had a relapse of fatty liver after 5 years, and sixty patients suffered other dis- ease. Comparing the two parts of patients, there was clear statistic difference （P（0. 01）. The recurrence and relative coinci- dence disease reduced obviously for the patients who insisted on non drug intervention. CONCLUSION There is very important clinical significance for the patients who insisted on using non drug intervention after full recovery to prevent fatty liver relapse and reduce the attack rate of relative disease.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
2014年第14期1193-1196,共4页
Chinese Journal of Hospital Pharmacy
基金
山西省科技攻关计划项目课题(编号:20090312023)
关键词
柴苓降脂方
脂肪肝
跟踪随访
非药物性干预
Chailingjiaangzhi decoction
hepatic adipose infiltration
follow up
non drug intervention
