摘要
目的探讨皮褶厚度及体脂率与呼吸暂停综合征（SAS）的关系，为预防SAS的发生提供科学依据。方法采用回顾性病例对照研究，所有研究对象均经多导睡眠图仪（PSG）检查，病例组50例患者按照睡眠呼吸暂停指数（AHI）≥10次／h作为诊断标准诊断为SAS。对照组为未患SAS的其他科室患者。采用一般健康状况调查表对研究对象进行调查。采用Logistic回归模型对患者皮褶厚度及体脂率与SAS关系的比值比（OR）及其相应的95％可信区间（CI）进行估计。结果病例组肱三头肌皮褶厚度（TSF）、肩胛下皮褶厚度（SSF）及体脂率均值均明显高于对照组，差异均有统计学意义（P〈0．05）。经单因素Logistic回归分析发现，SSF与SAS的发生呈显著正相关（OR=1．302。95％CI：1．023～1．916，P=0．003），随着体脂率的增加，发生SAS的危险性也会增加（OR=1．561，95％CI：1．170—2．069，P=0．013）。多因素Logistic回归分析的结果表明，TSF、SSF及体脂率是SAS的危险因素（OR=1．746，95％CI：1．168～2．614；OR=1．653，95％CI：1．187—2．308；OR=1．487，95％CI：1．074—1．934）。结论皮褶厚度及体脂率对SAS发生有较显著性的影响。
Objective To investigate the relationship between sleep apnea syndrome（SAS） and skinfold and body fat rate, and provide scientific evidence for the prevention of SAS. Methods A retrospective case-control study was conducted. All subjects were tested by PSG, the 50 patients with SAS in the observation group were confirmed by the AHI ≥ 10 times/h. The patients in control group were admit ted to the same hospital not related with SAS. for different diseases subjects were investigated using general health questionnaires. Logistic regression models were used to estimate the relationship between SAS and skinfold and body fat rate by the odds ratios （OR） and 95% confidence intervals （CI）. Results Triceps skinfold （TSF）, subscapular skinfold（ SSF）, and body fat rate in the observation group was significantly higher than that of the control group （ P 〈 0.05 ）. The results of univariate Logistic regression showed that SSF was positively correlated with SAS （ OR = 1. 302, 95% CI： 1. 023 - 1. 916, P =0. 003）. It also showed that the SAS risk increased with the body fat rate （ OR = 1. 561, 95% CI： 1. 170 - 2. 069, P = 0. 013）. The multiple Logistic regression analysis showed that TSF, SSF and body fat rate were risk factors of SAS （OR=1.746, 95% CI： 1.168-2.614; OR =1.653, 95% CI： 1.187-2.308; 0R=1.487, 95% CI： 1. 074 - 1. 934）. Conclusions Skinfold and body fat rate has significant impact on SAS.
出处
《中国实用医刊》
2014年第15期46-48,共3页
Chinese Journal of Practical Medicine
