摘要
目的探讨路易氏体痴呆(DLB)的临床和神经电生理特点。方法综合分析3例DLB患者的脑电图(EEG)、P300、视觉诱发电位(VEP)和临床表现。结果DLB的EEG特点为:早期出现优势节律慢化;慢波活动增加;阵发性慢波活动。P300潜伏期延长。VEP无特征性改变。波动性认知功能减退,生动的视幻觉,僵直性帕金森症状为DLB的主要临床特点。结论早期出现的EEG优势节律慢化和阵发性慢波活动有助于DLB的临床诊断。EEG动态观察,可能会获得更多有价值的EEG信息。
Objective To investigate the neuroelectrophysiological and clinical features in dementia with Lewy bodies(DLB).Methods Standard EEG recordings,P300and VEP from 3patients with DLB were studie d,as well as their clinical profiles.Results All patients showed a slowing of dominant frequen cy and an increasing of slow frequency activity in their EEG records.2patients had slow wave transient activity.Increase in P300latency was found in all 3patients,but VEP showed no characteristic changes.Fluctuating cognitive impairment,vivid visual hallucinations,rigid ity were the main clinical features i n DLB.Conclusions Early occurred slowing of dominant f requency and slow transient wave in EEG may be useful in the diagnosis of DLB.
出处
《中国临床康复》
CSCD
2002年第15期2206-2207,共2页
Chinese Journal of Clinical Rehabilitation
基金
军队"九五"课题资助(98M139)
