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普乐可复治疗慢性移植肾功能减退 被引量:2

Clinical application of FK506 in treatment of renal transplant recipients with chronic grafted renal dysfunction
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摘要 目的 :观察普乐可复 ( FK5 0 6)治疗慢性移植肾功能减退的疗效。方法 :选择尸肾移植术后6~ 34个月出现慢性肾功能异常的患者 2 4例 ,将原有以环孢素 A( Cs A)为主的免疫抑制方案替换成以 FK5 0 6为主的免疫抑制方案 ,观察肾功能变化。结果 :替换 FK5 0 6治疗 8~ 1 2周后 ,2 1例肾功能明显改善 ,其中 4例肾功能在 4周内恢复正常 ,3例效果不良 ,但血清肌酐 ( Cr)未呈上升趋势 ,总有效率 85 %。继续随访 6个月以上 ,移植肾功能稳定 ,亦未发生明显药物毒性作用。结论 :对慢性移植肾功能减退患者采用 FK5 0 6替换 Cs
出处 《吉林大学学报(医学版)》 CAS CSCD 北大核心 2002年第4期414-415,共2页 Journal of Jilin University:Medicine Edition
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