摘要
目的 了解老年患者抗生素相关腹泻 (AAD)的特征。方法 院内AAD患者 16 5例 (老年组 12 4例 ,非老年组 4 1例 ) ,记录腹泻特点、粪常规、粪培养及腹泻前抗生素使用情况。结果 ①AAD患者以稀水样便及粘液便为主要表现 ,老年组腹泻频率 >10次 /d者明显增多 ,较早出现 ,持续时间明显延长 ,伴随症状减少 ;②粪常规及普通培养无特殊表现 ,老年组检出真菌例数明显增加 ;③三代头孢菌素引起AAD者最多 ,预防性用药占半数以上。结论 老年患者使用抗生素后更易引起AAD ;控制广谱抗生素的使用 。
Objective To investigate the characteristics of antibiotic associated diarrhea(AAD) in elderly patients.Methods 165 cases of diarrhea in hospital were divided into two groups:elder group (n=124) and younger group (n=41),recording the character of diarrhea (frequency and symptoms,etc) and routine test culture of faeces.The kind and dosage of antibiotics used before diarrhea were also recorded.Results ①Clinical manifestations in most of the cases present with watery or mucus stool.The cases with frequent diarrhea above 10 times/day in the elder were more than the younger with earlier occurence,longer duration fever and abdominal symptoms;②There was no special finding in routine test and culture of faeces,fungi were more found in elder group;③The main antibiotics caused AAD was cefox.More than half of the cases were due to preventive drugs Conclusions It is easy that AAD occurs in the elder after antibiotic was used,with persistence duration and more frequency of stool.It is important to control the use of wide spectrum antibiotics.
出处
《北京医学》
CAS
北大核心
2002年第4期265-267,共3页
Beijing Medical Journal
