摘要
目的 研究短暂性脑缺血发作 (TIA)患者血浆纤溶功能的变化。方法 对 2 2例颈内动脉系统TIA患者血浆组织型纤溶酶原激活物 (t PA)及其快速抑制物 (PAI)的活性、D 二聚体 (D D)及纤维蛋白原 (FbG)含量进行检测 ,并与对照组进行比较。结果 TIA组血浆t PA活性明显低于对照组 (P <0 .0 5 ) ,而PAI活性和D D及FbG含量则明显高于对照组 (P <0 .0 5 )。结论 TIA患者存在血浆纤溶功能异常 。
Objective To study the alteration of plasma fibrinolytic function in patients with transient ischemic attack(TIA).Methods Activities of tissue type plasminogen activator(t PA) and plasminogen activator inhibitor(PAI) and contents of D dimeter(D D) and fibrinogen(FbG) were determined in 22 patients with TIA and compared with 22 normal controls.Results Plasma t PA activity level in TIA group was significantly lower than that in control group ( P <0.05).But the levels of PAI,D D and FbG in TIA group were significantly higher than those in control group ( P <0.05). Conclusions Abnormal fibrinolytic function may be an important factor of TIA recurrence in TIA patients.
出处
《北京医学》
CAS
北大核心
2002年第4期242-243,共2页
Beijing Medical Journal
