摘要
目的 探讨甲状腺相关眼病患者下直肌肥大引起复视的手术治疗时机及效果 ,并观察下直肌组织病理学改变。方法 对 11例因下直肌肥大致复视的甲状腺相关眼病患者行下直肌退后术 ,术中取下直肌标本行组织病理学检查 ,术后观察疗效。 结果 所有患者术后向下注视及水平注视复视症状消失 ,眼位基本正常。病理学检查见肌纤维僵硬 ,肌细胞退变、数目变少 ,肌内膜、肌束膜及肌外膜大量结缔组织增生 ,眼外肌增大。 结论 甲状腺相关眼病患者下直肌大量纤维结缔组织的增生、肌纤维的变性导致的舒缩功能的降低 ,可导致复视 ;
Objectives To investigate the timing and effect of surgical treatment of diplopia caused by hypertrophic inferior rectus in patients with Graves′ ophthalmopathy and pathologic changes of inferior recti Methods Eleven diplopic patients with restrictive superior motion and enlarged inferior recti confirmed by CT scan were collected, and the inferior recti were recessed Specimens of inferior recti obtained during operation were stained by HE?PAS and observed by light microscope Results There was no diplopia after operation when patients looked down and horizontally in eleven cases Eye position was normal HE and PAS stain showed stiffness of muscular fiber, small muscular cell with degeneration, obvious proliferation of fibrous tissue in endomysium, perimysium and epimysium, which enlarged extraocular muscle Conclusion Poor function of inferior recti due to enormous proliferation of fibrous tissue and degeneration of muscular fiber results in the occurrence of diplopia Recession of inferior recti can eliminate patients′ diplopia
出处
《中华眼科杂志》
CAS
CSCD
北大核心
2002年第8期470-471,W004,共3页
Chinese Journal of Ophthalmology
基金
卫生部科学研究基金资助项目 (98 1 12 9)
关键词
甲状腺相关眼病
复视
手术治疗
组织病理学
Graves′ disease
Inferior rectus muscle
Diplopia
Ophthalmologic surgical procedures
Pathology
