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胃肠内补液在老年非酮症糖尿病高渗性昏迷治疗中的应用 被引量:20

Effectiveness of fluid infusion through gastrointestinal tract for treating elderly patients with nonketotic hyperosmolar diabetic coma
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摘要 目的 探讨胃肠内补液对老年非酮症糖尿病高渗性昏迷 (NKHDC)的疗效。方法  15例NKHDC老年患者 ,8例采用胃肠内补液联合静脉补液的方法治疗 (胃肠内补液组 ) ,7例采用单纯性静脉补液法治疗 (常规治疗组 ) ,观察血生化及血渗透压等指标。结果 胃肠内补液组治疗 2 4h后的血糖、钾、钠、氯和血浆渗透压较治疗前明显下降 (P <0 .0 5 ) ,48h后恢复正常水平。与常规治疗组相比 ,胃肠内补液组的电解质和血浆渗透压较快恢复正常 ,患者清醒早 ,静脉补液量少 ,无一例发生脑水肿、肺水肿、溶血和低血钾等并发症。结论 对老年NKHDC患者采用胃肠内补液法简单易行。 Objective To appraise the effectiveness of fluid infusion through gastrointestinal tract for elderly patients with nonketotic hyperosmolar diabetic coma (NKHDC). Methods Eight NKHDC patients were given fluid by both gastrointestinal tract and intravenous infusion (gastrointestinal fluid infusion group). Another 7 NKHDC patients were given intravenous infusion only(control group). Biochemical parameters and plasma osmotic pressure were measured.Results The levels of blood glucose, potassium, sodium, chloride and plasma osmotic pressure decreased obviously after 24 hour treatment and returned to normal after 48 hour treatment in the gastrointestinal fluid infusion group. Compared with the control group, the eletrolytes and plasma osmotic pressure returned to normal and restored consciousness more quickly in the gastrointestinal fluid infusion group. No patients in the gastrointestinal fluid infusion group showed complications as cerebral edema, pulmonary edema, hemolysis or hypokalemia. Conclusion Fluid infusion by gastrointestinal tract for elderly patients with NKHDC is safe and effective.
出处 《上海医学》 CAS CSCD 北大核心 2002年第7期402-404,共3页 Shanghai Medical Journal
关键词 治疗 胃肠内补液 非酮症糖尿病高渗性昏迷 老年人 NKHDC Gastrointestinal fluid infusion Nonketotic hyperosmolar diabetic coma Elderly
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  • 1[1]Kitabchi AE, Muphy MB. Diabetic ketoacidosis and hyperosmolarhyperglycemic nonketotic coma. Med Clin North Am, 1988,72:1545-1563.
  • 2[2]Matz R. Hyperosmolar non-acidotic diabetes (NHAD). In: PorteD, Sherwin RS, eds. Ellenberg & Rifkins-Diabetes Melltus. 5thed. Appleton & Lange, A Simon & Schuster Compamy, 1997.
  • 3[3]Ennis ED. Diabetic ketoacid and the hyperglycemic hyperosmolarSyndrome. In: LeRoith D et al ed. Endocrinology and Metabolism3rd. McGraw-Hilline, Health Professions Divions Divion, NewYord, 1996. 1506-1521.

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