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大剂量纳络酮治疗重型颅脑损伤 被引量:5

Clinical Effect of Naloxone on Patients with Severe Craniocerebral Injury
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摘要 目的 探讨纳络酮对重型颅脑损伤患者的疗效 .方法 将同期收治的 6 0例重型颅脑损伤患者随机分为治疗组 (纳络酮治疗 )和对照组各 30例 .对两组患者的 GCS(格拉斯哥评分 )及 GOS(格拉斯哥预后评分 )计分进行对比分析 .结果 治疗组患者的 GCS计分及 GOS计分在治疗后及随访时均较对照组有所提高 ,结果有显著性差异 (P<0 .0 5 ) . To explore the therapeutic effection of naloxone on the treatment of patients of the severe with craniocerebral injury. 60 patients with severe brain injury were randomly divided into the treatment group (used with the naloxone)and the control group. GCS and GOS were analysed comparatively. In comparison with control group both of GCS and GOS were increased evidently in treatment group ( P <0.05). Early administration of high dose of naloxone is safe and more effective for the patients with severe craniocerebral injury.
出处 《科技通报》 北大核心 2002年第4期337-339,共3页 Bulletin of Science and Technology
关键词 颅脑损伤 纳络酮 Β-内啡肽 药物治疗 craniocerebral injury naloxone beta endorphin
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