摘要
本文应用体外细胞培养方法,研究了景德镇所属九个陶瓷矿山粉尘对细胞的毒性作用,采用细胞存活率、乳酸脱氢酶和细胞内钾含量三项指标进行观察。结果表明,各种粉尘对肺泡巨噬细胞均有不同程度的毒性。用定量的方法综合三项指标危害指数比较了不同陶瓷矿山粉尘的毒性作用。本研究对陶瓷矿山粉尘危害分级管理提供了理论及实际应用依据。
The cytotoxity of the dust from nine pottery and procelain mines of Jing De Zhen was studied by cell culture technique. The cell survival rate, LDH activity and intracellular K^+ were observed. The results showed that the cytotoxity in the pulmonary alveolar macrophages appeared to be varied with different kinds of dust. Based on those three indices, a comprehensive and quantitaiive index, called harmful index was suggested to compare the severity of the toxic action of the various dusts. This study seemed to be good for hazard rating in those mines both theoretically and pratieally.
出处
《职业医学》
1991年第5期265-267,320,共3页
China Occupational Medicine
关键词
陶瓷
细胞毒性
粉尘
危害指数
pottery and porcelain mines, cultured cell, harm index number
