摘要
目的 探讨东莨菪碱对急性脑缺血再灌注损伤的保护作用。方法 32例患者按顺序随机分为治疗组 (A组 )与对照组 (B组 )。A组 18例给予东莨菪碱 0 6～ 0 9mg加入 5 %GS2 5 0～ 5 0 0ml持续静滴 ,每日 <3mg ,疗程 5～ 7d。B组除不用东莨菪碱外 ,其他治疗同A组。 结果 A组治疗后显效 12例 ,有效 4例 ,无效 2例 ,总有效率 88 9%:B组有效率为 71 5 %,两组比较有显著性差异 ,P <0 0 5。结论 东莨菪碱对脑缺血再灌注损伤后脑功能的恢复有一定睥保护作用。
Objective Objective:To evaluate the protect effect of scopolamine to acute cerebral ischemia reperfusion injury.Methods thirty-two patients were divided randomly into the treatment group (A group) and the control group (B group). Eighteen patients of A group were given scopolamine 0.6～.09mg+5%GS 250～500 ml continuance mainline for five or seven days. Oneday's dosage was less than 3 mg. B group patients were treated as A group patients except without scopolamine.Results The evident effect of A group after treatment was twelve patients.The effective was four patients.The ineffective was two patients. The total virtual value was 88.9%. The total virtual value of B group was 71.5%.There wer signficantly differences between A and B. P<0.05.Conclusion The study clewed that the scopolamine had definite protect effect in the comeback of brain function to the patients of acute cerebral ischemia reperfusion injury.
出处
《济宁医学院学报》
2002年第2期18-19,共2页
Journal of Jining Medical University
