HLA-G与妊娠免疫
摘要
对近年来人白细胞G抗原(HLA-G)的结构、分布、在妊娠免疫中的作用及其与病理性妊娠关系的研究进展进行综合分析。发现HLA-G在妊娠免疫耐受的建立中起重要作用。HLA-G的表达及功能缺陷可能与病理性妊娠,如妊娠高血压综合征、习惯性流产、胎儿宫内发育迟缓等的发病机制有关。
出处
《国外医学(妇产科学分册)》
2002年第3期137-139,共3页
Foreign Medical Sciences(Obstet Gynecol Fascicle)
参考文献15
-
1Le Bouteiller P.HLA-G in the human placenta:expression and potential functions.Biochem Soc Trans,2000,28(2):208-212
-
2Tarrade A,Lai Kuen R,Malassine A,et al.Characterization of human villous and extravillous trophoblasts isolated from first trimester placenta.Lab Invest,2001,81(9):1199-1211
-
3Riteau B,Menier C,Khalil-Daher I,et al.HLA-G1 co-expression boosts the HLA class I-mediated NK lysis inhibition.Int Immunol,2001,13(2):193-201
-
4Ponte M,Cantoni C,Biassoni R,et al.Inhibitory receptors sensing HLA-G1 molecules in pregnancy:Inhibitory receptors sensing HLA-G1 molecules in pregnancy:CD94/NKG2A and acquire p49,an HLA-G1-specific receptor [see comments].Proc Natl Acad Sci USA,1999,96(10):5674-5679
-
5Kanai T,Fujii T,Kozuma S,et al.Soluble HLA-G influences the release of cytokines from allogeneic peripheralblood mononuclear ceils in culture.Mol Hum Reprod,2001,7(2):195-200
-
6Moreau P,Adrian Cabestre F,Menier C,et al.IL-10 selectively induces HLA-G expression in human trophoblasts and monocytes.Int Immunol,1999,11(5):803-811
-
7Hamai Y,Fujii T,Yamashita T,et al.The expression of human leukocyte antigen-G on trophoblasts abolishes the growth-suppressing effect of interleukin-2 towards them.Am J Reprod Immunol,1999,41(2):153-158
-
8Goldman-Wohl DS,Ariel I,Greenfield C,et al.Lack of human leukocyte antigen-G expression in extravillous trophoblasts is associated with pre-eclampsia.Mol Hum Reprod,2000,6(1):88-95
-
9O'Brien M,McCarthy T,Jenkins D,et al.Altered HLA-G transcription in pre-eclampsia is associated with allele specificinheritance:possible role of the HLA-G gene in susceptibility to the disease.Cell Mol Life Sci,2001,58(12-13):1943-1949
-
10Aldrich C,Verp MS,Walker MA,et al.A null mutation in HLA-G is not associated with preeclampsia or intrauterine growth retardation.J Reprod Immunol,2000,47(1):41-48
-
1余江,李大金.HLA-G在母胎界面中的免疫调节作用[J].国外医学(妇产科学分册),2002,29(3):140-142. 被引量:1
-
2余江.HLA-G在母胎界面中的免疫调节作用[J].福州总医院学报,2002,9(2):122-124.
-
3夏革清.一氧化氮与妊娠免疫[J].国外医学(免疫学分册),2000,23(6):351-353. 被引量:3
-
4盛秋,李芬.子宫自然杀伤细胞的研究进展[J].中国妇幼健康研究,2013,24(6):960-962. 被引量:3
-
5颜建华,吴建华,周光炎.妊娠免疫耐受机制[J].国外医学(免疫学分册),1998,21(1):14-17. 被引量:7
-
6邢丽霄,贺同强.子痫前期患者胎盘组织Fas/FasL的表达异常及意义[J].中国妇幼健康研究,2008,19(5):520-521.
-
7彭冰,刘淑芸.非经典人类白细胞抗原I类分子与妊娠免疫[J].中国妇幼健康研究,2006,17(3):190-193.
-
8夏革清.一氧化氮与妊娠免疫[J].国外医学(妇产科学分册),2000,27(1):20-23. 被引量:1
-
9刘志杰,刘淑芸.核因子-κB与妊娠[J].国外医学(妇产科学分册),2005,32(6):333-335. 被引量:4
-
10杨勉,赵亚丽,郝冬梅.HLA-G在妊娠中的研究进展[J].中国优生与遗传杂志,2009,17(1):113-115. 被引量:4