摘要
目的:研究壳聚糖溶液用作中药水提液澄清剂时的特点及相对于水提醇沉法所具有的优点。方法:以中药清热解毒处方为例,测定壳聚糖溶液粘度与澄清剂最少用量之间的关系;对经水提醇沉法和壳聚糖澄清法处理后的药液进行总黄酮含量的测定并对比。结果:随着壳聚糖溶液粘度的降低,澄清剂最少用量渐趋于一个恒定值;壳聚糖澄清法所得药液的总黄酮含量大于用水提醇沉法处理后的药液。结论:壳聚糖溶液是一个良好的中药水提液澄清剂,在使用过程中,粘度和用量是重要的影响因素。
AIM The purpose is to study the character of chitosan solution when it is used as clarifier for Chinese herbal medicine's water-extract. Also it was compared with EtOH to find which one is better for clarifying. METHODS Qingrejiedu prescription was used in this experiment. The relationship between viscosity of chitosan solution and minimal dosage of the clarifier was explored. Were measured and compared contents of general flavonoids in two samples which were respectively prepared with chitosan solution and EtOH. RESULTS With the viscosity reducing of chitosan solution, the minimal dosage goes to a constant. The content of general flavonoids of one sample which was clarified with chitosan solution was higher than that of the other one which was clarified with EtOH. CONCLUSION Chitosan solution is a good clarifier for Chinese herbal medicine's water-extract. In the course of using it, viscosity and dosage are two important factors.
出处
《江苏药学与临床研究》
2002年第2期23-25,共3页
Jiangsu Pharmacertical and Clinical Research
关键词
壳聚糖
澄清剂
中药水提液
粘度
总黄酮
有效成分提取
Chitosan
Clarifier
Chinese herbal medicine's water-extract
Viscosity
General flavonoids
