摘要
目的:建立高效液相色谱法测定阿苯达唑的含量。方法:采用Lichrospher 100 RP-18(5μm,250mm×4mm)柱。以甲醇-0.1 mol/L醋酸钠缓冲液(用醋酸调节pH=3.1)(60:40)为流动相,用紫外检测器于254nm波长处检测。结果:阿苯达唑浓度在0.1～0.8mg/ml范围内有较好的线性关系(r=0.9992),RSD=0.5％(n=6)。结论:本法快速简便,准确。
AIM The purpose is to determine the content of Albendazole by HPLC. METHODS Lichrospher100 RP-18(5 ×m, 250 m×4 mm)Column was used, methanol-0. 1 mol/L sodium acetate buffer (pH = 3. 1)(60: 40) served as mobile phase. It was detected at wavelength 254 nm with UV-detector. RESULTS Albendazole concentration presented a good linear relation within a range of 0. 1-0. 8 mg/ml, and the RSD-0. 5%(n = 6). CONCLUSION This method is rapid, simple, and accurate.
出处
《江苏药学与临床研究》
2002年第2期21-22,共2页
Jiangsu Pharmacertical and Clinical Research
