摘要
目的探讨不同启始时间应用颅脑降温治疗仪(电子冰帽)致头部轻度低温(亚低温)对高血压性脑出血预后的影响。方法72例高血压性脑出血患者随机分为治疗组和对照组,每组36例;每组再分为脑出血后第6、12和24h亚组,每亚组12例。在给予脑出血常规治疗的同时,治疗组使用电子冰帽。观察血肿体积、血肿周围水肿体积及神经功能缺损评分的变化。结果治疗后第7d与第21d的第6、12、24h开始致头部轻度低温的治疗组与相应时间的对照组血肿体积无显著性差异(P>0.05)。治疗后第21d的第6、12、24h启始的治疗组与相应时间的对照组血肿周围水肿体积比较有非常显著性差异(P<0.01)。治疗后第21d的第6、12h启始的治疗组与相应时间对照组神经功能缺损评分有非常显著性差异(P<0.01),第24h的两组间有显著差异(P<0.05)。结论第6、12和24h启始应用电子冰帽使头部轻度低温治疗高血压性脑出血,均能减轻血肿周围水肿,改善神经缺损功能,但对血肿的大小无影响。
Objective To evaluate the effects of selective onset times of mild hypothermia(MHT)with head temperature -control instrument (31-35℃)on the hypertensive intracerebral hemorrhage (HIH).Methods Seventy-two cases with HIH were randomly divided into treated group and control group,each group was thirty-six cases;each group were further divided into6,12and24hours subgroups,each subgroup were twelve cases.All cases of treated group were treated by selective head MHT with head temperature -control instrument.The volumes of hematoma and edema were measured by CT.Neurological deficiency score (NDS)were assessed separately.Results No difference was found in the volumes of hematoma between6,12,24hours groups in7th,21th days after the treatment and the control groups(P>0.05),respectively.The volumes of perihematomal edema decreased in6,12,24hours of the treated groups after treated21th day(P<0.01).Significant difference was found between6,12hours groups after treated21th day and control groups(P<0.01)in NDS.Difference was found between24hour s group after treated21th day and control group(P<0.05)in NDS.Conclusions The performing selective head MHT with head temperature-control instrument within24hours can reduce the perihematomal edema,improve the neurological function,not decrease the volume of hematoma of the patient with HIH.
出处
《实用医药杂志》
2002年第6期404-406,共3页
Practical Journal of Medicine & Pharmacy
关键词
脑出血
轻度低温
颅脑降温治疗仪
启始时间
Intracerebral hemorrhage Mild hypothermia Head temperature-control instrument Onset time
