摘要
目的 :探讨妊高征患者血浆纤维蛋白原和 D-二聚体的变化及临床意义。方法 :以 2 4例妊高征者 (妊高征组 ,其中重度妊高征 15例 ,轻、中度妊高征 9例 ) ,和正常妊娠妇女 2 0例 (对照组 )为观察对象 ,采用 PT导出纤维蛋白原测定法 (PT- der法 )定量检测血浆纤维蛋白原 ;采用乳胶凝集法半定量测定血浆 D-二聚体。结果 :重度妊高征患者血浆纤维蛋白原水平和 D-二聚体检测阳性率明显增高 (P<0 .0 5 ) ,但轻、中度妊高征患者与正常妊娠妇女间差异无显著性。结论 :血浆纤维蛋白原水平和 D-二聚体检测阳性率在妊高征患者明显升高 。
Objective:To investigate the changes and the clinical significance of plasma fibrinogen and D-dimer in patients with pregnancy induced hypertension(PIH).Methods:The level of plasma fibrinogen was measured by PT-deriving method and D-dimer was detected by the method of emulsion agglutination in 44 cases,including 24 normal pregnant women and 9 patients with mild and moderate PIH,15 patients with severe PIH.Results:The value of plasma fibrinogen and the positive rate of plasma D-dimer in severe PIH patients was markedly higher than that of mild and moderat PIH,as well as of normal pregnant women( P <0.05).Conclusion:The level of plasma fibrinogen and the positive rate of plasma D-dimer are higher in PIH than that in nomal pregnancy,and this increase is associated with the severeity of disease.
出处
《山西临床医药》
2002年第6期410-411,共2页
Shanxi Clinical Medicine
基金
山西省归国留学人员基金 (NO.0 0 5 1)
山西省教委基金 (NO.990 35 )资助
