摘要
前文报道了竹红菌素的结构修饰,本文继续报道竹红菌素和丙烯腈的β-腈乙基化反应。
β-cyanoethyl,β-carboxyethyl,and β-amidoethyl groups could be introduced to hypocrellin A(HA),hypocrellin B(HB),and one hypocrellin derivative 1 via Michael reaction with acrylonitrile.It is observed that oxygen was involved in the reaction.Under the sensitization with methylene bluc at λ>600nm,selective photooxygenation of 1 followed byreduction with P(OPh)_3 gives a hypocrellin derivative 7.In comparison with HA,thesederivatives appeared tO show comparable quantum yields for singlet oxygen formation,0.24±0.01.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
1991年第4期400-404,共5页
Chinese Journal of Organic Chemistry
基金
国家自然科学基金资助课题
部分测试由北京中关村地区联合分析测试中心基金
关键词
竹红菌素
β-腈乙基化
选择光氧化
hypocrellin pigments,β-cyanoethylation,selective photooxygcnation
