摘要
本文报道的236-1经肠全营养制剂,成分为低聚萄葡糖、乳化脂肪,可溶性蛋白质、12种维生素、矿物质和微量元素。大鼠分二组,先喂无氮饲料10天,使处于负氮平衡。之后,实验组喂制剂,对照组喂含15%酪蛋白的混合饲料。结果:二组大鼠体重都有增加;氮平衡和血清总蛋白都恢复到正常水平,其数值为实验组显著高于对照组;制剂中可溶蛋白的生物效价、净蛋白利用率、氮效能,也都高于混合饲料的酪蛋白。20例手术病人以本制剂作营养的唯一来源,每天摄入能量8033kJ,平均3.6天由负氮平衡转为正氮平衡。体重、血清总蛋白、白蛋白都有所增加。40例与饮食合用者也都增加,对瘘和切口的愈合效果尤为明显。腹泻发生率3.3%。
The composition, nutritional evaluation and clinical trials of a nutritionally complete enteral preparation were presented. It was composed of glucose oligosaccharides, emulsified fat, solubilized proteins, twelve vitamins, certain minerals and trace elements. Rats were forced to negative nitrogen balance by means of protein-free diet. Body weight and serum total protein declined accordingly. When the feed was changed to this preparation in one group, and a routine one with equal nitrogen content in another, nitrogen balance was turned to positive, body weight increased, serum total protein returned to normal in both groups. The increments of nitrogen balance and body weight were, however, higher significantly in the group fed with the preparation than that with routine diet. The biological value, net protein utilization and protein efficiency ratio of the solubilized proteins in the preparation were higher than casein in the routine feed. Twenty surgical patients having the preparation as the sole source of nutrients could take around 8.37MJ(2000 kcal)a day. Nitrogen balance turned from negative to positive in an average time of 3.6 days. Body weight, serum total protein, serum albumin were all increased. Fourty patients took this as dietary supplement and the similar results were observed too. Clinical effects were excellent in all cases, especially for healing of surgical wounds and fistula. Incidence of diarrhea was 3.3%.
出处
《营养学报》
CAS
CSCD
北大核心
1991年第1期1-8,共8页
Acta Nutrimenta Sinica
关键词
经肠全营养制剂
营养评价
total enteral nutrient preparation nutritional evaluation