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肝移植病人围术期低氧血症的防治

The change of respiratory function and prevention of hypoxemia of orthotopic liver transplantation during perioperative period
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摘要 目的:探讨肝移植病人围术期影响呼吸功能的因素以及对低氧血症的预防和治疗措施。方法 :回顾性分析了 3例背驮式原位肝移植 (POL T)患者的临床资料 ,对肝移植病人围术期发生的呼吸功能不全的原因进行分析。 结果:围术期存活 2例 ,死亡 1例。术后并发急性呼吸衰竭、感染、急性排斥反应、肾衰等。结论:减少外科手术并发症是提高肝移植患者手术成功率以及长期存活的关键 ;呼吸“泵”衰竭是低氧血症形成的重要原因之一 ; Objective: To study factors affecting respiratory function and prevention of hypoxemia in the patients with liver transplantation during perioperative period. Methods: Three patients with end staged liver diseases underwent liver transplantation between June 2000 and Feb 2001 were retrospectively analyzed. Prevention of respiratory function disorder and hypoxemia were systematically assessed during postoperative management. Results: Two patients survived for more than one month. Another patient died within 30 days from multiple organ failure after POLT. Major complications were respiratory failure? primary hepatic nonfunction? infection ?acute rejection and acute renal failure. Conclusion: Technical aspects of the operation are the most critical determinants of early outcome. Respiratory 'pump' failure is one of important causes for hypoxemia. Mechanical ventilation and oxygen treatment are an effective approach in liver transplantations.
出处 《新疆医科大学学报》 CAS 2002年第2期126-126,共1页 Journal of Xinjiang Medical University
关键词 机械通气 低氧血症 肝移植 呼吸衰竭 mechanical ventilation hypoxemia liver transplantation respiratory failure
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