摘要
目的探讨食管裂孔疝患者食管蠕动功能的改变在胃食管反流中的意义。方法选择32例有胃食管反流症状患者(单纯食管裂孔疝10例、食管裂孔疝合并食管炎12例、单纯食管炎10例)和9例无反流症状的对照组,分别测定其下食管括约肌(LES)压力、食管的蠕动波幅、蠕动时限、蠕动速度,并经内镜对患者食管炎的程度进行分级。结果裂孔疝合并食管炎组、单纯食管炎组其LES压力较对照组均降低,单纯裂孔疝组LES压力较对照组降低,但无统计学差异。食管近端及远端的蠕动波幅食管裂孔疝组最高,达(51.3±5.4)mmHg和(83.6±8.3)mmHg,食管炎组最低;食管近远端的蠕动时限各组间无统计学差异;而食管远端的蠕动速度裂孔疝组也最高,食管炎组低于对照组。结论食管裂孔疝患者食管蠕动功能在胃食管反流、粘膜损伤的发生发展中起着重要的作用。
Objective To investigate the significance of changes of esophageal peristalsis in hiatal hernia patients. Methods 32 patients with symptom of gastroesophageal reflux(esophageal hernia 10, hiatal hernia with esophagitis 12 and esophagitis 10) and 9 patients without symptom of reflux were selected.Lower esophageal sphincter (LES) pressure ,esophageal peristaltic velocity ,amplitude and duration were detected respectively;the degree of esophagitis was identified with gastroscopy. Results LES pressures in hiatal hernia with esophagitis group and simple esophagitis group were significantly lower than those in control group , there was no significant difference between hiatal hernia group and control group . In hiatal hernia group ,the peristaltic amplitudes of proximal and distal esophagus (51.3±5.4 mmHg and 83.6±8.3 mmHg) were significantly higher than those in the other three groups , while esophagitis group was significantly the lowest . There were no significant difference about esophageal peristltic duration both of proxmial and distal esophagus between these four groups .Furthermore , distal esophageal peristaltic velocity was significantly higher in hiatal hernia group than that in the other three groups , and it was the lowest in esophagitis group .Conclusion The changes of esophageal peristalsis in patient with hiatal hernia play an important role in the pathogenesis of gastroesophageal reflux and mucosal injury.[
出处
《中华消化内镜杂志》
2002年第3期159-161,共3页
Chinese Journal of Digestive Endoscopy
