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准分子激光角膜切削术后3年临床疗效分析 被引量:4

An analysis of the therapeutic effects of excimer laser 3 years after photorefractive keratectomy
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摘要 目的 :探讨PRK术后 3年疗效及其相关影响因素。方法 :对接受PRK手术的 131只术眼进行了 3年的跟踪观察 ,将术眼按术前屈光度分为 3组 ,中低度组 (43眼 ) :- 6 .0D以下 ;高度组 (6 5眼 ) :- 6 .2 5~ - 10 .0D ;超高度组 (2 3眼 ) :- 10 .2 5D以上。对各组术后裸眼视力、眼压、角膜曲率、残余屈光度及haze的变化进行了分析。结果 :①术后视力 ,各组均比术前有显著性改善 (P <0 .0 1) ,中低度组术后半年即趋于平稳 (P >0 .0 5 ) ,高度及超高度组术后 2年视力均有回退 (P <0 .0 1)。②术后眼压 ,各组均比术前明显降低 (P<0 .0 5 ) ,中低度组术后半年趋于平稳 ,高度及超高度组术后1年趋于平稳。③术后角膜曲率 ,各组均比术前有显著性减少 (P <0 .0 1)。④术后残余屈光度 ,中低度组 1年后趋于平稳 ,高度和超高度组术后 2年趋于平稳。⑤haze ,中低度组在1年时已基本消失 ,高度及超高度组比中低度组消失晚。结论 :PRK手术对中低度、高度及超高度近视均有明显的疗效 。 Objective:To evaluate the therapeutic effects and factors related to excimer laser 3 years after photorefractive keratectomy.Methods:67 patients(131 eyes),whose ages ranged from 18 to 45 years,were selected for the study. All patients had undergone PRK 3 years earlier,and their eyes had been examined at one month,six months,one year,two years and three years after PRK. All of the patients selected for the study had complete medical records. The eyes were divided into three groups:the refractive error range for the first group was -0.5~-6.0 D(43 eyes),the second group,-6.25~-10.0 D(65 eyes),and the third group,-10.25~-14.5 D(23 eyes). Changes in visual acuity,tension,mean residual refraction,haze and keratometric power were analyzed at different time periods after PRK.Results:Visual acuity improved after PRK(P<0.01) for all patients compared to their visual acuity before PRK. Visual acuity for the first group stabilized after 6 months(P>0.05),but the visual acuity for the second group showed improvement for the first year(P<0.01) and then worsened(P<0.01). Visual acuity for the third group improved for 6 months(P<0.01) and then worsened(P<0.01). Tension changes were different for the three groups. In the first group,tension increased rapidly in the first month(P<0.01),reached its highest level at the end of the first month,then decreased gradually(P<0.05),stabilizing after one year. In the second group,tension increased rapidly during the first 6 months(P<0.05),reached its highest level at the end of six months,then gradually decreased(P<0.05),stabilizing after 2 years(P>0.05). Tension for the third group changed in the same manner as for the second group. Eye drops mixed with corticosteroid caused changes in tension. After PRK,the keratometric power for the three groups decreased in the first month compared to keratometric power before PRK(P<0.01),then gradually increased for 6 months,stabilizing after 6 months(P>0.05). Changes in mean residual refractions were different for the three groups. In the first group,mean residual refraction stabilized after 1 year and in the second and third groups,it stabilized after 2 years. In the first group,haze disappeared after 1 year,and in the second and third groups,haze disappeared after 2 years.Conclusion:PRK is an effective and safe refractive surgery for treating myopia(-0.5~-14.50 D). The effect of PRK was better for low refractive errors(-0.50~-6.0 D) than for high refractive errors(-6.25~-14.50 D). From this research,we can assume that the long term effectiveness of PRK is satisfactory.
作者 李丽 张月梅
出处 《眼视光学杂志》 2002年第2期86-89,共4页 Chinese Journal of Optometry & Ophthalmology
关键词 准分子激光角膜切削术 疗效分析 屈光矫正手术 photorefractive keratectomy myopia/surgery therapeutic effects
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