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血浆血小板激活因子酰基脱水酶与心血管疾病

Platelet-Activating Factor Acetylhydrolase and Cardiovascular Disease
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摘要 血小板激活因子 (PAF)为强有力的炎症介导剂 ,PAF酰基脱水酶 (PAF AH )能水解PAF使其失活 ,在一些心血管疾病中起重要作用 ,如在缺血与再灌注 (I/R)中起保护作用 ,也与冠心病、动脉粥样硬化、腹主动脉瘤。 Platelet activating factor(PAF) is one of the most potent inflammation mediators.PAF acetylhydrolase(PAF AH) hydrolyze PAF and render it inactive.PAF AH plays an important role in some cardiovascular disease.For example,playing a protective role in ischemia reperfusion injury,and have close relation to coronary heart disease,atherosclerotic occlusive disease,abdominal aortic aneurysm,nonfamilial dilated cadiomyopathy and the state of the perioperative period of patients undergoing cardiac surgery.
作者 姚道阔
机构地区 泰山医学院附属医院心血管内科
出处 《现代诊断与治疗》 CAS 2002年第4期232-234,共3页 Modern Diagnosis and Treatment
关键词 血小板激活因子 心血管疾病 血小板激活因子酰基脱水酶 血浆 PAF PAF-AH Cardiovascular disease Platelet activating factor acetylhydrolase Blood plasma
分类号 R54 [医药卫生—心血管疾病]
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参考文献18

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现代诊断与治疗
2002年 第4期

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