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大鼠胃肠道Cajal间质细胞的超微结构研究 被引量:8

The ultrastructure character of Cajal interstitial cell of rat gastrointestinal tract
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摘要 目的 明确大鼠胃肠道Cajal间质细胞的超微结构特点。方法 选用健康成年雄性SD大鼠的胃窦、小肠、结肠组织 ,进行透射电镜观察。结果 大鼠Cajal间质细胞的主要结构特点为 :完整的基膜 ,丰富的沿细胞膜分布的小空泡 ,细胞质内细胞器丰富 ,以线粒体最显著 ,异染色质较多 ,沿核膜分布 ,Cajal间质细胞之间、与神经元细胞、肌细胞之间形成很多的缝隙连接。结论 Cajal间质细胞具有独特的超微结构特点 ,易于识别 ,且其超微结构特点与其功能相适应。 Aim To study the ultrastructure character of Cajal interstitial cell of rat gastrointestinal tract.Methods Tissues of gastric antrum?small intestine?colon of healthy adult male SD rat were observed through electric telescope.Re sults The main character of Cajal interstitial cells of rat were numerous small vacuoles scattered along cell membrane,integrated basal lamina,abundant organelles compacted in cytoplasm,among them the mitochondrion was the most notable,heterochromatism distributed along nuclear membrane was the major,many gap junctions were formed between Cajal interstitial cells and neuron cells,between Cajal interstitial cells and myocyte,and between themselves.Conclusions Cajal interstitial cells have unique ultrastructure character.It is easy to identify them,furthermore,its ulrtastructure character is suitalble with its functions.
出处 《胃肠病学和肝病学杂志》 CAS 2002年第2期112-114,共3页 Chinese Journal of Gastroenterology and Hepatology
关键词 大鼠 CAJAL间质细胞 超微结构 Rat Cajal interstitial cell Ultrastructure
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参考文献4

  • 1[1]Hagger R,Finlayson C,Jeffrey I,et al.Role of the interstitial cells of Cajal in the contral of gut motility.Br Sur,1997,84(4): 445-50.
  • 2[2]Liu LW,Thuneberg L,Huizinga JD.Selective lesioning of interstitial cells of Cajal by methylene blue and light leads to loss of slow waves.Am J Physiol 19 94, 266L(3Pt1): 485-96.
  • 3[3]Hagger R,Finlayson C,Jeffrey I.Role of the interstitial cells of Cajal in the control of gut motility.Br J Surg,1997,84(4): 445-50.
  • 4[4]Kenny S.E,Connell M.G,Rintala R.J,et al.Abnormal colonic interstitial cel ls of Cajal in children with anorectal malformations.J Pediatr Surg,1998,33(1): 130-2.

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