摘要
从华北白前(Cynanchum hancockianum)中分离到4个新三萜类化合物,通过光谱分析(~1HNMR,^(13)CNMR,2DNMR,MS,X-Ray)及化学相关等分别鉴定为华北白前醇(hancockinal,Ⅰa).新自前醇(hancolupenoI,Ⅱd),新白前酮(hancolupenone,Ⅱc)及新白前醇二十八烷酸酯(hancolupenol octacosanate,Ⅱd),均为新型骨架的化合物。
Four new triterpenoids have been isolated from the petroleum ether extract of Cynanchum hancockianum (Maxim)Al. Iljinski (Asclepiadaceae). On the basis of spectral data (~1HNMR, ^(13)CNMR, ~1H-~1H COSY, ~1H-^(13)C COSY, longrange ~1H-^(13)C COSY, MS, X-Ray analysis) and chemical connections, they were identified as hancockinol (Ⅰa), hancolupenol (Ⅱa), hancolupenone (Ⅱc), and hancolupenol octacosanate (Ⅱd). They are of new skeletons with B/C cis, C/D trans, D/E cis junctures for Ⅰa and with A/B trans, C/D trans, D/E cis junctures for Ⅱa, Ⅱc and Ⅱd.
出处
《药学学报》
CAS
CSCD
北大核心
1991年第8期584-592,共9页
Acta Pharmaceutica Sinica
关键词
华北白前
三萜
新白前醇
Cynanckum hancockianum
Triterpenoids
Hancockinol
Hancolupenol
Hancolupenone
Hancolupenol octacosanate
