摘要
用肝硬化大鼠动物模型,观察了肝硬化大鼠不同时期门脉血流动力学与胰高糖素的关系。肝硬化大鼠的血清胰高糖素显著增高,早期尤为明显;同时,门脉血流量和门脉压力也明显上升。提示在门脉高压症发病机制中,胰高糖素对门脉高压症的形成起了重要作用。
Serum glucagon level and portal hemodynamic alteration in development of experimental liver cirrhosis was investigated. Serum glucagon increased significantly when cirrhosis is developing at the initial stage, portal blood flow volume and pressure increased concommitantly. Glucagon might play an important role in the pathogenesis of portal hypertension. '
出处
《湖南医科大学学报》
CSCD
1989年第4期382-384,共3页
Bulletin of Hunan Medical University
关键词
肝硬变
门脉高压症
胰高糖素
动物
liver cirrhosis, experimental
portal hypertension
glucagon
etiology
rats
