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子宫颈癌前和癌变患者血清标记物的研究 被引量:1

A SURVEY OF TUMOR MARKERS IN PATIENTS WITH SQUAMOUS CELL CANCER AND PRECANCER OF UTERINE CERVIX
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摘要 检测65例子宫颈癌前病变和癌变患者与102例正常对照组的SF、β-hCG、CEA、及AFP水平。结果实验组SF、β-hCG及CEA均显著高于对照组,并随子宫颈癌临床期别增高而升高;AFP在两组之间差异无显著性。SF、β-hCG及CEA诊断子宫颈癌的可用度分别为53.4%、55.7%、53.5%,三项指标联合应用的可用度可提高到70.0%。但无助于早期癌肿诊断。 The circulating levels of serum ferritin ( SF) , beta-subunit human chorionic gonadotropin (β-hCG), carcinoembryonic antigen (CEA) and α-fetoprotein (AFP) in 65 patients and 102 healthy person as control were studied. The mean value of SF, β-hCG and CEA was significantly higher in patients than in control (P< 0.01), but there was no significant difference in AFP between these two groups ( P> 0.05) . The levels of SF, β-hCG and CEA rose as the stage of cervical cancer progresses.The availabilities of SF, β-hCG and CEA used in diagnosis of cervical cancer were 53.4%, 55.7% and 53.6% respectively, and was 70.0% when they were used in combination. However, they seem to be not helpful in the early diagnosis of cervical cancer.
出处 《湖南医科大学学报》 CSCD 1989年第2期179-182,共4页 Bulletin of Hunan Medical University
关键词 宫颈癌 血清 标记物 鳞状细胞 cervix neoplasms carcinoma, squamous cell ferritin gonadotropins, chorionic carcinoembryonic antigen fetal proteins blood diagnosis
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