摘要
ELISA检测免疫家兔刺破晶状体后血清晶状体抗体的动态变化,同时用Digeon改良法测定血清IC,发现发病组家兔血清IC刺后1周至3周比耐受组低,有显著性差别(0.05>P>0.01),而晶状体抗体刺后1周明显增高。发病组刺后2周和3周呈下降趋势,耐受组无变化,推测实验性晶状体过敏性色素膜炎的发生可能与晶状体抗体的适量产生和局部IC沉积有关,并对该病发生的免疫耐受作一讨论。
The changes of serum crystallin antibody in immunized rabbits with injuried lens were measured by ELISA. At the same time, circulating immune complexes were detected with Digeon improving method. It was found that the CIC at one to three week of uveitis group is less than that of no uveitis group (0.05>p>0.01). The titers of crystallin antibody at the one week after injuring was obviously increased, The titers of crystallin antibody in uveitis group was decreased at two and three week, no uveitis group was no change. It is suggested that the occurrence of experimental lens-induced uveitis might be related to suitable production of crystallin antibody and local deposition of IC.
出处
《眼科研究》
CSCD
1991年第1期36-38,共3页
Chinese Ophthalmic Research
关键词
葡萄膜炎
晶状体
抗体
兔
IC
uveitis, serum crystallin antibody, rabbit.
