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脑卒中危险因素的病例对照研究 被引量:5

A case-control study of risk factors for stroke
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摘要 [目的 ] 进一步探索脑卒中的危险因素 ,特别是可干预的危险因素 ,为积极预防和控制脑卒中的发生提供依据。  [方法 ] 根据上海市 4家地段医院脑卒中报病新发病例 ,按年龄、性别和相同居委配对要求 1∶1选取对照 ,开展病例对照研究 ,采用条件Logistic回归模型进行统计分析。 [结果 ] 高血压史、常吃咸食、经常性紧张、性格急躁四项危险因素进入了多因素条件Logistic回归模型 ,其OR值分别为 7.73( 95 %CI 4.78~ 12 .49)、3.0 4( 95 %CI 1.6 3~ 5 .6 8)、2 .74( 95 %CI 1.5 4~ 4.89)和 2 .92 ( 95 %CI 1.2 7~ 6 .74)。  [结论 ] 对于脑血管疾病的防治需采取综合干预措施 ,包括控制高血压 ,改变不良的生活方式和饮食习惯 ,以及注意劳逸结合 ,保持良好的精神状态。 To further explore the risk factors for stroke,especially the changeable ones,in order to prevent and control the occurrence of stroke. A 1∶1 matched case-control study was used and the conditional logistic regression model was performed in this study.The cases were those new stroke patients registered in four community hospitals in Shanghai,the controls were selected by the same gender and neighborhood,and each pair's ages was permitted to differ within 5 years. Hypertension,more salt intake,stress and precipitancy entered the multiple conditional logistic regression model,and their ORs were 7.73(95%CI 4.78~12.49),3.04(95%CI 1.63~5.68),2.74(95%CI 1.54~4.89) and 2.92(95%CI 1.27~ 6.74 ),respectively. [Conclusion] It's necessary to implement a comprehensive prevention program,such as hypertension control, lifestyle and dietary habit modification, more attentions to between work and relax, and good psychosis preservation.
出处 《上海预防医学》 CAS 2002年第6期256-257,262,共3页 Shanghai Journal of Preventive Medicine
基金 上海市医学发展基金重点研究课题项目 (98ZD0 0 1 )
关键词 脑卒中 危险因素 病例对照研究 条件LOGISTIC回归 干预措施 Stroke Risk factor Case-control study Conditional logistic regression
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参考文献8

  • 1王文志.卒中流行病学与人群防治.见:张国瑾,赵增荣主编.国外脑血管疾病研究进展.北京:中国医药科技出版社,2000.177-207
  • 2吴卫平.脑血管病的危险因素和脑血管病的遗传学[M]..脑血管病学[C].北京:人民军医出版社,1999.166-187.
  • 3Gorelick PB, Sacco RL, Smith DB, et al. Prevention of a first stroke:a review of guidelines and a multidisciplinary consensus statement from the National Stroke Association. JAMA, 1999, 281 (12): 1112~ 1120
  • 4Stegmayr B, Asplund K, Kuulasmaa K, et al. Stroke incidence and mortality correlated to stroke risk factors in the WHO MONICA Project. An ecological study of 18 populations. Stroke, 1997, 28(7) : 1367~ 1374
  • 5Antikainen RL, Jousilahti P, Vanhanen H, et al. Excess mortality associated with increased pulse pressure among middle- aged men and women is explained by high systolic blood pressure. J Hypertens, 2000, 18(4) :417~423
  • 6Kannel WB. Fifty years of Framingham Study contributions to understanding hypertension. J Hum Hypertens, 2000, 14(2) :83~90
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  • 8Kannel WB. Risk stratification in hypertension:new insights from the Framingham Study. Am J Hypertens, 2000, 13(1 Pt 2) :3S~ 10S

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