摘要
采用JL - 0 2多位点探针和Southern杂交对Wistar大鼠基因组进行了DNA指纹分析 ,并对国内最具有典型的 6个地区 9个Wistar大鼠群体内和群体间进行了DNA指纹分析比较。结果表明 ,DNA指纹图较好地反映了封闭群动物的遗传本质 ,具有良好的多态性。同一群体不同个体间Wistar大鼠遗传距离主要为 0 .2～ 0 .6 ,将不同群体的Wistar大鼠DNA指纹图带进行分析表明 ,所有群体间的DNA指纹图的遗传距离在 0 .2～ 0 .7。
DNA fingerprinting of Wistar rat were studied with JL-02 Mulilocus probe and Southern hybridization,and comparing with different individuals of nine groups Wistar rat from six national classical area and different groups.It was indicated that DNA fingerprinting could reflect genetic material of outbred strain rat,and were more polymorphic.The genetic distances of Wistar rat were distributed for 0.2～0.6 among different individuals within same groups,and the genetic distances of Wistar rat were distributed for 0.2～0.7 among different groups.
出处
《遗传》
CAS
CSCD
北大核心
2002年第3期275-278,共4页
Hereditas（Beijing)
基金
总后卫生部基金课题资助 ( 98M 116 )
