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肽核酸的固相合成方法 被引量:1

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摘要 肽核酸 (PNA)作为一类很有发展前景的非天然的反义核酸 ,其高效合成是将其广泛应用的基础。
作者 王文浩
出处 《国外医学(药学分册)》 2002年第3期129-134,共6页 Foreign Medical Sciences(Section of Pharmarcy)
基金 国家重点基础研究发展规划项目 (G19980 5 1114 )
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同被引文献9

  • 1de la Torre BG, Eritja R. Synthesis of labelled PNA oligomers by a post-synthetic modification approach [ J]. Bioorg Med Chem Lett, 2003, 13 (3): 391-393.
  • 2Yuan X, Ma Z, Zhou W, et al. Lipid-mediated delivery of peptide nucleic acids to pulmonary endothelium [J]. Biochem Biophys Res Commun, 2003, 302 (1): 6 - 11.
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  • 9Egholm M, Buchardt O, Christensen L, et al. PNA hybridizes to complementary oligonucleotides obeying the WatsonCrick hydrogen-bonding rules [ J ]. Nature, 1993,365 (6 446) :5 66 - 568.

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