摘要
目的 :观察阿托品不同给药方式对重度急性有机磷农药中毒 (AOPP)的治疗效果。方法 :随机将 12 2例AOPP患者分为 A、B两组 ,A组 6 3例反复静推阿托品达阿托品化后 ,采用微量泵持续静脉输注 ;B组 5 9例采用反复静推阿托品 ,将治疗前后的疗效、阿托品用量及用药天数进行比较。结果 :阿托品用量及用药天数两组间无明显差异。A组治愈率 (96 .82 %)明显高于 B组 (83.0 5 %) (P<0 .0 5 ) ,死亡率 (3.17%)、阿托品中毒发生率 (1.6 %)、脑水肿发生率 (1.6 %)低于 B组 (P<0 .0 5 )。A组反跳的发生率低于 B组 (P<0 .0 1)。结论 :反复静推阿托品达阿托品化后 ,采用微量泵持续静脉输注阿托品治疗 AOPP效果明显。
Objective:To observe the therapeutic efficacy of atropin in the patients with serious acute organophosphorus pesticide poisoning(AOPP).Methods:122 cases of AOPP were randomly divided into A and B group.In the group A(63 cases) the intravenous injection of atropin was be given repeatly until aropinization,then the intravenous infusion of atropin was be given by infusion pump.In the group B (59 cases) the intravenous injection of atropin was be given repeatly.Compared the account of atropin,days of application of atropin and the theraputic effect of the two groups before and after treatment.Result:The account of atropin and days of application of atropin between two groups are not different.Cure rate(96.82 %) of group A is higher than group B (83.05 %)(P<0.05).Death rate (3.1 %),incidence rate of atropinism(1.6 %) and incidence rate of hydrocephalus(1.6 %) of group A are lower significantly than group B(P<0.05).Incidence rate of hydrocephalus(1.6 %) of group A are lower significantly than group B(P<0.05).Conclusion:The therapentic efficancy of combining intravenous injection of atropin with intravenous infusion of atropin is very good.
出处
《山西临床医药》
2002年第5期331-332,共2页
Shanxi Clinical Medicine
