摘要
目的 观察化学药物联合免疫调节剂治疗难治、复治肺结核的临床效果。方法 2 2 6例涂阳病人随机分为治疗组及对照组 ,两组化疗方案相同 ,治疗组加用卡介菌多糖核酸 ,观察疗效。结果复治涂阳治疗组痰菌阴转率 80 .0 % ,对照组 6 5 .2 % ;其中耐多药结核病治疗组痰阴转率 6 1.5 % ,对照组 16 .7%。经统计学处理皆有显著性差异 (P <0 .0 5 )。结论 治疗组疗效明显优于对照组 ,化学药物联合免疫调节剂是治疗耐多药结核病及其他难治。
Objective To observe the curative effect of the retreated pulmonary tuberculosis patients chemotherapy combined with immune regulation preparation.Methods 226 smear-positive cases were divided into trial group and control group at random.All patients were treated by the same chemotherapy regime,but the trial group was assistantly treated by immunotherapy with BCG vaccine polysaccharide nucleic acid (BCG-PSN).The effect was compared between the two groups.Results At the end of the course,the sputum negative conversion rates of the retreated pulmonary tuberculosis of the trial group and the control group were 80.0% and 65.2% respectively.As for MDR pulmonary tuberculosis,the rates were respectively 61.5% and 16.7% for the trial group and the control group.The information above was singnificant in statistics (P<0.05).Conclusion The curative effect in the trial group was obvious superior to the control group.As indicated the immunotherapy was more effective in treating the retrated pulmonary tuberculosis.
出处
《中国防痨杂志》
CAS
北大核心
2002年第3期137-139,共3页
Chinese Journal of Antituberculosis
