摘要
目的比较静脉注射与静脉入壶前列腺素E1(Lipo PGE1)治疗糖尿病肾病 (DN)的疗效。方法选择我院DN患者 79例 ,随机分为 2组 ,分别采取静脉注射、静脉入壶二种途径应用Lipo PGE1治疗 ,每日 10 μg ,共用 14天。检测、比较治疗前后 2 4h尿微量白蛋白排泄率 (UAE)。结果静脉注射与静脉入壶Lipo PGE1治疗DN前后UAE减少均有统计学意义 (P <0 .0 5 )。静脉注射组UAE下降 4 3.19± 13.35 % ;静脉入壶组UAE下降 37.0 0± 13.6 3% ;二组比较差异有显著意义 (P <0 .0 5 )。结论静脉注射与静脉入壶途径应用Lipo PGE1能有效降低DN的UAE。静脉注射疗效要好于静脉入壶 ,而且节约医疗资源 ,治疗时间短 ,减少病人痛苦及不必要的液体输注 。
Objectives To compare the curative effect of diabetic nephropathy (DN) treated by vein injection and vein infusion prostaglandin E1(PGE1).Method 79 cases of patients with DN were selected and divided into two groups, and were treated through vein injection and vein infusion prostaglandin E1 respectively. the dosage is 10 μg daily for 14 days. Urine albumin excretion (UAE) were tested and compared between the two group. Result there are significantly difference in the reducing of UAE of DN patients after treated by vein injection and vein infusion prostaglandin E 1. ( P <0.05). the reducing of UAE for vein injection PGE1 group was 43.19±13.35%, for vein infusion prostaglandin E1 group was 37.00±13.35%, there are significantly difference between the two group( P >0.05). Conclusion The UAE of DN patient can be reduced through vein injection and vein infusion prostaglandin E1. The curative effect for vein injection is better than vein infusion prostaglandin E 1, which is economy, shorter time , less pain and easy to use during clinical treatment.
出处
《护士进修杂志》
北大核心
2002年第6期408-409,共2页
Journal of Nurses Training
