摘要
本文用彩色多普勒超声心动图检测100例(20～76岁)正常人舒张功能,按低龄(20～35岁)、中龄(36～50岁)、高龄(>51岁)分为三组。测量二尖瓣多普勒血流频谱①EA 两峰时间—速度积面(T—A);②分别测量 E、A 峰时间—速度积面(F—A)、(A—A)及舒张期前1/2时间—速度积面(50%)(T—A)。心尖四腔或左室二腔切面测量舒张末期左室容积(V)或左室长轴切面、M 型取腱索水平测舒张末期最大内径及二尖瓣短轴切面的(?)口面积。计算下列7项指标。(1)峰值充盈速率(ml/s)PFR;(2)校正峰值充盈速率(Sec^(-1))NPFR;(3)半充盈分数1/2 FF;(4)舒张早期快速充盈的减速度(cm/s^2)DEF;(5)A 峰值速度/E峰值速度 A/E;(6)A 峰时间—速度积面/E 峰时间—速度积面 A—A/E—A;(7)A 峰时间—速度积面/总积面 A—A/T—A。上述所测数据,发现正常人左室舒张功能随年龄增长而改变。舒张早期与 E 峰有关测值随年龄增长而降低(PFR、NPFR、1/2 FF、DEF);舒张晚期与 A 峰有关测值随年龄增长而升高(A/E、A—A/E—A、AA/T—A)。经统计学处理后各组值间有显著差异或非常显著差异(P<0.05或0.001)这一特征与创伤性检查相一致。说明正常人左室舒张功能和顺应性有随着年龄增长而有“衰变”的趋势,这一“衰变”在50岁以上显得明显。多普勒测量左室舒张功能比 M 型敏感。
The left ventricular diastolic function was studied with 2D color Doppler
echocardiography in 100 healthy persons (age range 20-76 years)who were divided
into three groups:Group 1,20-35 years old;Group 2,36—50 years old;Group 3,
more than 51 years old.The following seven indexes were measured and calculated
in the images of mitral Doppler flow spectrum:1,Peak filling rate (in ml/sec,
PFR)was determined as the peak early diastolic velocity times the cross-sectional
area of mitral opening;2,Normalized peak filling rate(in sec^(-1),NPFR)was
determined as the peak filling rate divided by the left ventricular end-diastolic
volume (PFR/EDV);3,Half filling fraction was determined as the TVI (time
velocity integral) at one half diastolic filling period divided by the total diastolic
TVI (1/2TA/TA);4,Early diastolic filling fallen velocity (in cm/s^2,DFF);
5,Velocity of peak A/velocity of peak E (A/E);6,TVI of peak A/TVI of
peak E(A-A/E-A );7,TVI of peak A/total TVI (A-A/T-A).The measure-
ment showed that the left ventricular diastolic function changed with age increased
The data of early diastolic period in connection with peak E (PFR,NPFR,1/2FF,
DEF) decreased and that of late diastolic period in connection with peak A (A/E,
A-A/E-A,A-A/T-A)increased with growing,in the results of three groups measu-
rement appeared marked or very marked difference(P less than 0.05 or 0.01)in stat- istics and was as same as that by invasive examination.The data showed the attenuated
tendency of the left ventricular diastolic function and compliance following person
growth,in particular at the age over 50 years.The early diastolic filling peak
reduced and A/E,A-A/E-A,A-A/T-A ratio increased because increase of left
atrial power and left ventricular compliance decreased influenced mitral spectrum
showed the cases of peak A more than peak E were 30 of 100 cases (30%) and
the cases of peak A=peak E were 28 cases (28%).In B-mode ultrasonography
mitral peak A and peak E of these cases didn't appeared A more than E except
EFV falling,so left ventricular diastolic function measured by Doppler was more
sensitive than by B-mode ultrasonography.
出处
《现代诊断与治疗》
CAS
1991年第1期20-24,共5页
Modern Diagnosis and Treatment
