摘要
目的 探讨放疗在骶尾部脊索瘤临床治疗中的作用。方法 采用常规分段治疗。第—段DT40Gy/ 2 0次 /4周 ,休 2周 ;第二段DT3 0GY / 15次 / 3周。随访 5年。结果 16例骶尾部脊索瘤术后放疗或单纯性姑息放疗 ,不仅可使术后复发明显减少 (本组术后放疗复发率为 15 .3 8% ) ,而且使术后遗留症状得到改善 ,甚至消失。大剂量分段放疗的患者均未发生放射性损伤。结论 手术后放疗或单纯姑息性放疗能有效控制瘤体生长 ,延长生存期。文献提出脊索瘤对放射线不敏感的说法是否准确值得进一步探讨。
Objective To discuss and explore the clinical effect of radiotherapy for chordoma in sacrum caudal region.Methods Routine fraction radiotherapy:Primary stage:DT 40GY/20 times/4 weeks, 2 weeks of interval;Second stage:DT 30GY/15 times/3 weeks,5 years′ follow up.Results By analysing 13 cases of postoperative radiotherapy for chordoma in sacurm caudal region and 3 cases of single palliative radiotherapy,we found that it could not only obviously decrease the rate of post operative reurrence,but also improve the post operative symptoms,sometimes even no symptoms were found. In these 16 cases,the recurrence rate was 15.38%. No radioactivity damage was found after the large dose fraction radiotherapy.Conclusion Post operative radiotherapy or single palliative radiotherapy can effectively suppress the growth of chordoma and prolong the patients′ survival time.The opinions that chordoma in sacurm caudal region are insensitive to radioactive rays need to be further discussed.
出处
《中国肿瘤临床与康复》
2002年第2期63-64,共2页
Chinese Journal of Clinical Oncology and Rehabilitation
