摘要
目的 对不同危险层的高血压患者进行CRP检测 ,探讨CRP在动脉粥样硬化 (AS)疾病中的临床意义。方法 高血压 3级具有很高危病人 4 5例和高血压 1级中危病人 30例 ,测CRP ,TC ,TG ,并结合颈动脉内 -中膜厚度超声检查作对照分析。结果 高血压 3级很高危一组CRP平均为 35 .4 9± 19.12mg/L ,高血压 1级中危病人的CRP平均<8mg/L(P <0 0 0 1)。高血压 3级很高危组TC平均为 6 .5 1± 1.6 8mmol/l,高血压 1级中危对照组的TC平均为 4 .0 7± 0 88mmol/l,高血压 3级很高危组TG平均为 2 .0 5± 1.4 9,高血压 1级中危组TG平均为 1.31± 0 39,P <0 0 5。高血压 3级很高危组的颈动脉内 -中膜厚度 (IMT)为 1.0 3± 0 2 9mm ,高血压一级中危对照组IMT为 0 81± 0 2 2mm ,P <0 0 5。结论 CRP含量如同TC ,TG ,IMT一样与高血压患者中的动脉粥样硬化程度相关。
Aim To survey the relationship between the serum C Reactive Protein(CRP) level and atherosclerostic indexes in hypertensive patients. Methods CRP,total cholesterol(TC),triglyceride(TG) and carotid intima media thickness were examined in 75 hypertensive patients(1st stage hypertension,\%n\%=30 and 3rd stage hypertensive,\%n\%=45). Results The CRP level was 35.49±19.12 mg/L in the 3rd stage hypertensive patients,but less than 8 mg/L in first stage hypertensives. The TC and TG levels in the 3rd stage hypertensives were higher than those in the first stage hypertensives(6.51±1.68 mmol/L vs 4.07±0 88 mmol/L and 2.05±1.49 mmol/L vs 1.31±0 39 mmol/L,respectively). The carotid intima medium thickness(IMT) of carotid was thicker in the 3rd stage hypertensive than that in the first stage hypertensives(1.03±0 29 mm vs 0 81±0 22 mm). Conclusion The serum CRP level is positively related to the atherosclerostic indexes in hypertensive patients.
出处
《高血压杂志》
CSCD
2002年第3期255-256,共2页
Chinese Journal of Hypertension
关键词
高血压病
C-反应蛋白
动脉粥样硬化
血胆因醇
血甘油三酯
Atherosclerosis
CRP
Hypertension
Total cholesterol
Triglyceride
Intima medium thickness of carotid
